SCHEMBL7947156

SCHEMBL7947156

CC1(C)CC2(CC(C)(C)c3ccc(OCC4CO4)cc32)c2cc(OCC3CO3)ccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
TP53 P04637 3/20 0.51
TSHR P16473 3/20 0.51
HIF1A Q16665 2/20 0.51
CYP3A4 P08684 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
PPARG P37231 4/20 0.47
MAPT P10636 3/20 0.47
HPGD P15428 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CYP1A2 P05177 1/20 0.47
TDP1 Q9NUW8 1/20 0.45
PKM P14618 2/20 0.45
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
FGFR1 P11362 1/20 0.39
SRC P12931 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18942232 0.99 ALDH1A1 (0.50) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL14725203 0.96 ALDH1A1 (0.53) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL20371234 0.86 ALDH1A1 (0.39) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL14725207 0.86 ALDH1A1 (0.43) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL7956106 0.84 ALDH1A1 (0.45) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL14725210 0.82 TSHR (0.52) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL14725209 0.82 TSHR (0.52) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL7955961 0.78 ALDH1A1 (0.46) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL20012998 0.76 TSHR (0.36) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL1495871 0.76 GRM2 (0.57) ALDH1A1TP53TSHRHIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8092231-A None JP disclosed
EP-3504283-B1 SOLID HOMOGENEOUS AMORPHOUS HIGH HEAT EPOXY BLENDS, ARTICLES, AND USES THEREOF SHPP GLOBAL TECH BV (NL) 2021-04-07 EP disclosed
US-10870724-B2 High heat monomers and methods of use thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-12-22 US disclosed
US-20200263052-A1 SOLID HOMOGENEOUS AMORPHOUS HIGH HEAT EPOXY BLENDS, ARTICLES, AND USES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-08-20 US disclosed
EP-3640275-A1 CURABLE EPOXY COMPOSITIONS AND CURED PRODUCTS THEREOF SABIC Global Technologies B.V. (NL) 2020-04-22 EP disclosed
US-10472467-B2 Polymers having intrinsic microporosity including sub-units with troger's base and spirobisindane moieties DOW GLOBAL TECHNOLOGIES LLC (US) 2019-11-12 US disclosed
US-10465037-B2 High heat monomers and methods of use thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-05 US disclosed
US-20190322653-A1 METHODS FOR SYNTHESIZING HIGH PURITY EPOXY COMPOUNDS AND PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-10-24 US disclosed
US-20190211151-A1 POLYMERS HAVING INTRINSIC MICROPOROSITY INCLUDING SUB-UNITS WITH TROGER'S BASE AND SPIROBISINDANE MOIETIES DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-11 US disclosed
WO-2019035054-A1 SOLID HOMOGENEOUS AMORPHOUS HIGH HEAT EPOXY BLENDS, ARTICLES, AND USES THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-02-21 WO disclosed
WO-2018058116-A1 HIGH HEAT AND HIGH TOUGHNESS EPOXY COMPOSITIONS, ARTICLES, AND USES THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-03-29 WO disclosed
US-20170158806-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-06-08 US disclosed
US-20170158806-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-06-08 US disclosed
WO-2016014536-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-01-28 WO disclosed
US-6169158-B1 HAVING A GLASS TRANSITION TEMPERATURE HIGHER THAN 20 DEGREES CELCIUS, BASED ON POLYFUNCTIONAL 1,1'-SPIROBIINDANS AND/OR 3,3',4,4'-TETRAHYDRO-2,2'-SPIROBI(2H-1-BENZOPYRAN); CURABLE, POWDER COATINGS VANTICO, INC. 2001-01-02 US disclosed
EP-1015440-A1 POLYGLYCIDYL SPIROCOMPOUNDS AND THEIR USE IN EPOXY RESINS Ciba SC Holding AG (CH) 2000-07-05 EP disclosed
US-6080833-A BIS(HYDROXYALKOXYLATED) 1,1'-SPIROBIINDAN POLYCARBONATES AND POLYESTERS POLYMERS AND CURABLE COMPOUNDS SUCH AS BIS(ACRYLATED ALKOXY)SPIROBIINDANS; ALSO POLYAMIDES AND POLYIMIDES CONTAINING SPIROBIINDAN GROUPS MITSUI CHEMICALS, INC. (JP) 2000-06-27 US disclosed
WO-1999003851-A1 POLYGLYCIDYL SPIROCOMPOUNDS AND THEIR USE IN EPOXY RESINS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-01-28 WO disclosed
EP-0822545-A2 Optical component and spirobiindan polymer therefor MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-02-04 EP disclosed
JP-H0892231-A SPIROBIINDAN DIGLYCIDYL ETHER AND ITS PRODUCTION MITSUI TOATSU CHEM INC 1996-04-09 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10870724-B2 High heat monomers and methods of use thereof HSP90AA1, HSP90AB1, EPHX2 ALDH1A1 318/4885TP53 710/4885TSHR 4879/4885
US-20170158806-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF HSP90AA1, HSP90AB1, EPHX2 ALDH1A1 318/4885TP53 710/4885TSHR 4879/4885
US-10465037-B2 High heat monomers and methods of use thereof HSP90AA1, HSP90AB2P, HSP90AB1 ALDH1A1 295/4885TP53 794/4885TSHR 4878/4885
US-20190322653-A1 METHODS FOR SYNTHESIZING HIGH PURITY EPOXY COMPOUNDS AND PRODUCTS OBTAINED THEREFROM EPHX2, EPHX1, CYP2F1 ALDH1A1 138/4885TP53 3230/4885TSHR 4683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.