Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | TACR2 | P21452 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958311 | 0.90 | HRH1 (0.58) | HRH1TACR2TACR1EDNRBEDNRA | |
| SCHEMBL8308100 | 0.82 | TACR1 (0.61) | TACR2TACR1 | |
| SCHEMBL27385927 | 0.79 | HRH1 (0.39) | HRH1EDNRBEDNRAHTR1D | |
| SCHEMBL8885371 | 0.78 | TACR2 (0.53) | HRH1TACR2TACR1 | |
| SCHEMBL8592345 | 0.77 | TACR2 (0.65) | HRH1TACR2TACR1 | |
| SCHEMBL8883479 | 0.77 | TACR2 (0.65) | HRH1TACR2TACR1 | |
| SCHEMBL8884449 | 0.77 | TACR2 (0.55) | HRH1TACR2TACR1 | |
| SCHEMBL8882191 | 0.77 | TACR2 (0.54) | HRH1TACR2TACR1 | |
| SCHEMBL8882429 | 0.77 | TACR2 (0.65) | HRH1TACR2TACR1 | |
| SCHEMBL8885397 | 0.77 | TACR2 (0.53) | HRH1TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |