Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.47 |
| ▸ | ACACB | O00763 | 6/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25015826 | 0.83 | NOTUM (0.57) | USP30ACACBNTSR1NOTUM | |
| SCHEMBL18929109 | 0.83 | ADRA2C (0.50) | USP30ACACBNTSR1NOTUMADORA2A | |
| SCHEMBL20004371 | 0.82 | BPTF (0.57) | USP30ACACBNTSR1ADORA2ABPTF | |
| SCHEMBL3121487 | 0.82 | USP30 (0.47) | USP30ACACBNTSR1NOTUMADORA2A | |
| SCHEMBL13486520 | 0.80 | NOTUM (0.50) | USP30ACACBNTSR1NOTUM | |
| SCHEMBL25015825 | 0.79 | NOTUM (0.60) | USP30ACACBNOTUMADORA2A | |
| SCHEMBL38659895 | 0.77 | ACACB (0.45) | USP30ACACBNTSR1 | |
| SCHEMBL6467831 | 0.76 | AR (0.48) | NOTUMBPTF | |
| SCHEMBL3174270 | 0.76 | USP30 (0.45) | USP30ACACBNOTUM | |
| SCHEMBL21874744 | 0.76 | MAPT (0.51) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021797-A1 | CONDENSED HETEROCYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |