Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996780 | 0.94 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTHRH1KCNH2 | |
| SCHEMBL7947626 | 0.90 | KDM4E (0.39) | ALDH1A1KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL7958360 | 0.90 | MEN1 (0.40) | ALDH1A1KDM4EHTTMAPTL3MBTL1 | |
| SCHEMBL7954527 | 0.89 | KDM4E (0.41) | ALDH1A1KDM4EHTTHRH1KCNH2 | |
| SCHEMBL6996096 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTHRH1KCNH2 | |
| SCHEMBL6992507 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4EHTTHRH1KCNH2 | |
| SCHEMBL6997482 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KDM4EHTTHRH1KCNH2 | |
| SCHEMBL7956429 | 0.87 | MEN1 (0.39) | ALDH1A1KDM4EHTTSMN1; SMN2THRB | |
| SCHEMBL7495346 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4EHTTHRH1KCNH2 | |
| SCHEMBL7982215 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KDM4EHTTHRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |