Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1528661 | 0.89 | SMN1; SMN2 (0.56) | HTR7KDM4EALDH1A1SMN1; SMN2ADRB2 | |
| SCHEMBL7944215 | 0.80 | HTR7 (0.70) | HTR7KDM4EALDH1A1SMN1; SMN2ADRB2 | |
| SCHEMBL1249856 | 0.79 | MEN1 (0.45) | KDM4ESMN1; SMN2ADORA3ALOX15RAB9A | |
| SCHEMBL1528432 | 0.78 | HSD17B10 (0.63) | KDM4EALDH1A1SMN1; SMN2ADORA3ALOX15 | |
| SCHEMBL6670234 | 0.78 | HTR7 (0.67) | HTR7KDM4EALDH1A1SMN1; SMN2ADRB2 | |
| SCHEMBL29904797 | 0.78 | HTR7 (1.00) | HTR7KDM4EALDH1A1SMN1; SMN2ADRB2 | |
| SCHEMBL7937912 | 0.78 | PTPN1 (0.76) | HTR7KDM4EALDH1A1SMN1; SMN2ADRB2 | |
| SCHEMBL7949356 | 0.77 | HTR7 (0.65) | HTR7KDM4EALDH1A1SMN1; SMN2ADRB2 | |
| SCHEMBL17279908 | 0.76 | NPC1 (0.48) | KDM4EALDH1A1SMN1; SMN2ADORA3ALOX15 | |
| SCHEMBL1528540 | 0.76 | HTR7 (0.59) | HTR7KDM4EALDH1A1SMN1; SMN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |