Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948523 | 0.93 | EDNRA (0.59) | EDNRAEDNRB | |
| SCHEMBL6641032 | 0.81 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL7949423 | 0.80 | EDNRA (0.68) | EDNRAEDNRB | |
| SCHEMBL6640197 | 0.75 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6642697 | 0.74 | EDNRA (0.68) | EDNRAEDNRB | |
| SCHEMBL6777867 | 0.74 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL6151288 | 0.74 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6766562 | 0.72 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL4764193 | 0.72 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL7947185 | 0.71 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033886-A1 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-18 | — | — | WO | claimed |
| WO-2001049289-A1 | PHARMACEUTICAL AND VETERINARY USES OF ENDOTHELIN ANTAGONISTS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-07-12 | — | — | WO | disclosed |