Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 17/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956819 | 0.99 | HRH1 (0.49) | HRH1TACR1MAPK1 | |
| SCHEMBL7956245 | 0.96 | HRH1 (0.50) | HRH1TACR1 | |
| SCHEMBL7955924 | 0.94 | HRH1 (0.51) | HRH1TACR1 | |
| SCHEMBL7956187 | 0.93 | HRH1 (0.49) | HRH1TACR1SSTR5 | |
| SCHEMBL7947451 | 0.89 | SSTR5 (0.44) | HRH1SSTR5 | |
| SCHEMBL7958381 | 0.85 | KMT2A (0.45) | HRH1SSTR5 | |
| SCHEMBL1387145 | 0.84 | HRH1 (0.53) | HRH1TACR1SSTR5 | |
| SCHEMBL1388865 | 0.83 | HRH1 (0.52) | HRH1TACR1 | |
| SCHEMBL7961463 | 0.82 | HRH1 (0.51) | HRH1TACR1SSTR5 | |
| SCHEMBL7962558 | 0.82 | HRH1 (0.50) | HRH1TACR1SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |