Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 11/20 | 0.50 |
| ▸ | P2RX2 | Q9UBL9 | 10/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.50 |
| ▸ | CTSA | P10619 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171499 | 0.90 | P2RX3 (0.61) | P2RX3P2RX2NR1I2 | |
| SCHEMBL2171032 | 0.85 | P2RX3 (0.49) | P2RX3P2RX2NR1I2CTSACYP2C9 | |
| SCHEMBL2187309 | 0.82 | P2RX3 (0.56) | P2RX3P2RX2NR1I2CTSACYP2C9 | |
| SCHEMBL2172363 | 0.82 | P2RX3 (0.49) | P2RX3P2RX2NR1I2CTSACYP2C9 | |
| SCHEMBL2172956 | 0.81 | NR1I2 (0.45) | P2RX3P2RX2NR1I2CTSA | |
| SCHEMBL2170986 | 0.80 | NR1I2 (0.45) | P2RX3P2RX2NR1I2CTSA | |
| SCHEMBL2171462 | 0.79 | P2RX3 (0.53) | P2RX3P2RX2NR1I2 | |
| SCHEMBL2171457 | 0.79 | P2RX3 (0.53) | P2RX3P2RX2NR1I2 | |
| SCHEMBL2174361 | 0.78 | P2RX3 (0.48) | P2RX3P2RX2NR1I2 | |
| SCHEMBL2171711 | 0.75 | CYP3A4 (0.46) | P2RX3P2RX2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |