SCHEMBL7947539

SCHEMBL7947539

O=C1C=CC2=C(C1)CC(O)C2

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.40
GSK3B P49841 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9529683 0.75 GSK3A (0.40) GSK3AGSK3B
Hydrochloric Acid SCHEMBL11349506 0.68 GSK3A (0.33) GSK3AGSK3B
SCHEMBL7359397 0.65 MBTD1 (0.31) GSK3AGSK3B
SCHEMBL11958254 0.64
SCHEMBL1200455 0.63 GSK3A (0.32) GSK3AGSK3B
SCHEMBL943110 0.62 GSK3A (0.46) GSK3AGSK3B
SCHEMBL10790767 0.62 GSK3A (0.46) GSK3AGSK3B
SCHEMBL9527717 0.62 GSK3A (0.46) GSK3AGSK3B
SCHEMBL277815 0.61
SCHEMBL30766303 0.61 GSK3A (0.43) GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6262113-B1 HYDROXY- OR MERCAPTO-PHENYLUREAS SMITHKLINE BEECHAM CORPORATION 2001-07-17 US disclosed
US-6005008-A IL-8 receptor antagonists SMITHKLINE BEECHAM CORPORATION (US) 1999-12-21 US disclosed
US-5886044-A IL-8 receptor antagonists SMITHKLINE BEECHAM CORPORATION (US) 1999-03-23 US disclosed
US-5780483-A IL-8 receptor antagonists SMITHKLINE BEECHAM CORPORATION (US) 1998-07-14 US disclosed