Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811269 | 0.90 | LMNA (0.44) | KMT2AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6811238 | 0.88 | LMNA (0.46) | KMT2AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7785810 | 0.81 | MAPT (0.44) | KMT2AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7782560 | 0.79 | KMT2A (0.49) | KMT2AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6819407 | 0.78 | MEN1 (0.56) | KMT2AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6810888 | 0.78 | LMNA (0.51) | KMT2AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6811176 | 0.78 | LMNA (0.54) | KMT2AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6810882 | 0.75 | LMNA (0.49) | KMT2AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6816443 | 0.74 | LMNA (0.52) | KMT2AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6814765 | 0.74 | LMNA (0.42) | KMT2AALDH1A1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |