SCHEMBL7947874

SCHEMBL7947874

NC(Cc1ccc(O)c(O)c1)C(=O)OCC(=O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.60
ESR2 Q92731 1/20 0.60
SLC7A5 Q01650 6/20 0.58
KDM4E B2RXH2 1/20 0.58
USP2 O75604 1/20 0.58
EGFR P00533 1/20 0.58
LCK P06239 1/20 0.58
FYN P06241 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
ALOX15 P16050 1/20 0.58
PTGS1 P23219 1/20 0.58
HTR2A P28223 1/20 0.58
PTGS2 P35354 1/20 0.58
RECQL P46063 1/20 0.58
HIF1A Q16665 1/20 0.58
HSD17B10 Q99714 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
KDM6B O15054 1/20 0.46
ERCC1 P07992 2/20 0.45
ERCC4 Q92889 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16944293 0.85 SLC7A5 (0.55) ESR1ESR2SLC7A5PTGS1MAPT
SCHEMBL11508934 0.85 KDM4E (0.67) ESR1SLC7A5KDM4EUSP2EGFR
SCHEMBL11440820 0.82 SLC7A5 (0.63) SLC7A5KDM4EUSP2EGFRLCK
SCHEMBL31453291 0.82 SLC7A5 (0.63) SLC7A5KDM4EUSP2EGFRLCK
SCHEMBL1070495 0.82 SLC7A5 (0.63) SLC7A5KDM4EUSP2EGFRLCK
Hydrochloric Acid SCHEMBL4126484 0.81 SLC7A5 (0.61) SLC7A5KDM4EUSP2EGFRLCK
Hydrochloric Acid SCHEMBL4188588 0.81 SLC7A5 (0.61) SLC7A5KDM4EUSP2EGFRLCK
SCHEMBL1893385 0.81 SLC7A5 (0.55) ESR1ESR2SLC7A5KDM4EUSP2
SCHEMBL28726263 0.80 SLC7A5 (0.63) ESR1SLC7A5KDM4EUSP2EGFR
SCHEMBL8740352 0.79 SLC7A5 (0.58) ESR1SLC7A5KDM4EUSP2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6258854-B1 KETONE ETHERS FOR ODORS GIVAUDAN ROURE ( INTERNATIONAL ) SA (CH) 2001-07-10 US disclosed
CN-1248569-A Novel ketone GIVAUDAN ROURE INTERNATION SA (CH) 2000-03-29 CN disclosed
EP-0983990-A2 Ketones useful as precursors for organoleptic compounds Givaudan Roure (International) S.A. (CH) 2000-03-08 EP disclosed