Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959852 | 0.84 | ALOX15 (0.62) | SLC7A5TDP1KDM4EUSP2EGFR | |
| SCHEMBL22959859 | 0.84 | ALOX15 (0.62) | SLC7A5TDP1KDM4EUSP2EGFR | |
| SCHEMBL16135503 | 0.84 | ALOX15 (0.62) | SLC7A5TDP1KDM4EUSP2EGFR | |
| SCHEMBL7947874 | 0.81 | ESR1 (0.60) | SLC7A5TDP1KDM4EUSP2EGFR | |
| SCHEMBL8257343 | 0.81 | ALOX15 (0.57) | SLC7A5TDP1KDM4EUSP2EGFR | |
| SCHEMBL1068518 | 0.81 | ALOX15 (0.57) | SLC7A5TDP1KDM4EUSP2EGFR | |
| SCHEMBL3411781 | 0.80 | SLC7A5 (0.51) | SLC7A5TDP1KDM4EUSP2EGFR | |
| SCHEMBL10318019 | 0.80 | SLC7A5 (0.51) | SLC7A5TDP1KDM4EUSP2EGFR | |
| SCHEMBL3412205 | 0.80 | SLC7A5 (0.51) | SLC7A5TDP1KDM4EUSP2EGFR | |
| SCHEMBL2311992 | 0.80 | SLC7A5 (0.51) | SLC7A5TDP1KDM4EUSP2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056240-A2 | PHARMACEUTICAL COMPOSITIONS AND ORAL DOSAGE FORMS OF A LEVODOPA PRODRUG AND METHODS OF USE | XENOPORT, INC. (US) | 2011-05-12 | — | — | WO | disclosed |