SCHEMBL7948037

SCHEMBL7948037

O=C1c2ccccc2C(=O)c2c1cccc2-c1[c]cccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.48
ALDH1A1 P00352 7/20 0.44
L3MBTL1 Q9Y468 6/20 0.44
MAPK1 P28482 6/20 0.44
MAPT P10636 6/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
EGFR P00533 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
RAB9A P51151 2/20 0.44
LMNA P02545 2/20 0.44
PABPC1 P11940 1/20 0.44
CDC25B P30305 1/20 0.44
NSD2 O96028 1/20 0.44
MAOA P21397 7/20 0.42
MCL1 Q07820 3/20 0.42
ALOX12 P18054 2/20 0.42
BCL2 P10415 2/20 0.42
CYP3A4 P08684 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9335085 0.77 MEN1 (0.67) ADORA2AALDH1A1L3MBTL1MAPK1MAPT
SCHEMBL5010110 0.77 MEN1 (0.67) ADORA2AALDH1A1L3MBTL1MAPK1MAPT
SCHEMBL29836726 0.77 MEN1 (0.67) ADORA2AALDH1A1L3MBTL1MAPK1MAPT
SCHEMBL9041566 0.76 TDP1 (0.45) ALDH1A1L3MBTL1TDP1KDM4EHPGD
SCHEMBL695387 0.75 GSK3B (0.47) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL2761711 0.75 MEN1 (0.32) ALDH1A1L3MBTL1MAPK1MAPTSMN1; SMN2
SCHEMBL322239 0.73 MEN1 (0.35) ALDH1A1L3MBTL1MAPK1MAPTSMN1; SMN2
SCHEMBL8855149 0.73 MEN1 (0.35) ALDH1A1L3MBTL1MAPK1MAPTSMN1; SMN2
SCHEMBL10505006 0.72 HDAC4 (0.38) ALDH1A1MAPK1MAPTSMN1; SMN2MEN1
SCHEMBL9390578 0.72 ADORA2A (0.50) ADORA2AALDH1A1L3MBTL1MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6258503-B1 MELT PROCESSABILITY OF POLYMER DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2001-07-10 US disclosed