Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855149 | 1.00 | MEN1 (0.35) | MEN1KMT2AMAPK1KDM4ECES2 | |
| SCHEMBL2761711 | 0.97 | MEN1 (0.32) | MEN1KMT2AMAPK1KDM4ECES2 | |
| SCHEMBL2448843 | 0.89 | ALDH1A1 (0.38) | MAPK1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL769410 | 0.85 | ALDH1A1 (0.39) | MAPK1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL668821 | 0.83 | POLB (0.38) | MAPK1KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL11552312 | 0.82 | — | — | |
| SCHEMBL115447 | 0.82 | CYP3A4 (0.33) | SMN1; SMN2 | |
| SCHEMBL11721275 | 0.82 | — | — | |
| SCHEMBL9729872 | 0.81 | — | — | |
| SCHEMBL2154273 | 0.80 | ALDH1A1 (0.44) | MAPK1KDM4ENPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021223-A1 | CHEMICAL AGENTS CAPABLE OF FORMING COVALENT 3-D NETWORKS | OXFORD ADVANCED SURFACES LTD. (GB) | 2012-01-26 | — | — | US | disclosed |
| EP-2403825-A1 | CHEMICAL AGENTS CAPABLE OF FORMING COVALENT 3-D NETWORKS | Oxford Advanced Surfaces Ltd (GB) | 2012-01-11 | — | — | EP | disclosed |
| WO-2011030108-A1 | JMJD2 DEMETHYLASE INHIBITORS | ISIS INNOVATION LIMITED (GB) | 2011-03-17 | — | — | WO | disclosed |