Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | GJB2 | P29033 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955938 | 0.93 | NT5E (0.56) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7955939 | 0.93 | NT5E (0.56) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7955508 | 0.92 | NT5E (0.55) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7955504 | 0.92 | NT5E (0.55) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7948307 | 0.91 | NT5E (0.64) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7948306 | 0.91 | NT5E (0.64) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7959448 | 0.90 | NT5E (0.55) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7959453 | 0.90 | NT5E (0.55) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL8317281 | 0.89 | NT5E (0.54) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7948095 | 0.89 | NT5E (0.54) | NT5ESSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |