Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.64 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.41 |
| ▸ | CDC25B | P30305 | 6/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948306 | 1.00 | NT5E (0.64) | NT5EGJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL7959239 | 0.95 | NT5E (0.59) | NT5EGJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL7955504 | 0.93 | NT5E (0.55) | NT5EGJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL7955508 | 0.93 | NT5E (0.55) | NT5EGJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL7955938 | 0.92 | NT5E (0.56) | NT5EGJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL7955939 | 0.92 | NT5E (0.56) | NT5EGJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL7948100 | 0.91 | NT5E (0.55) | NT5EGJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL7959453 | 0.91 | NT5E (0.55) | NT5EGJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL7959448 | 0.91 | NT5E (0.55) | NT5EGJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL7962382 | 0.89 | NT5E (0.52) | NT5EGJB2SSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |