SCHEMBL7948165

SCHEMBL7948165

Cc1ccc(C2(COC(=O)Cc3ccc(F)cc3)CC2)c(OC(=O)C(C)C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.51
KMT2A Q03164 7/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.38
ALOX15 P16050 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
KLK7 P49862 2/20 0.35
ABL1 P00519 1/20 0.34
RIN1 Q13671 1/20 0.34
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
LMNA P02545 1/20 0.34
ADRB2 P07550 1/20 0.34
ADRA2A P08913 1/20 0.34
DRD2 P14416 1/20 0.34
ADRA2C P18825 1/20 0.34
DRD1 P21728 1/20 0.34
ADRA1A P35348 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7951730 0.90 NPSR1 (0.40) NPSR1KMT2APOLBAPEX1ATM
SCHEMBL7949206 0.90 NPSR1 (0.53) NPSR1KMT2APOLBAPEX1ATM
SCHEMBL7941788 0.86 NPSR1 (0.48) NPSR1KMT2APOLBAPEX1ATM
SCHEMBL7953533 0.86 NPSR1 (0.72) NPSR1KMT2APOLBAPEX1ATM
SCHEMBL7953545 0.79 KMT2A (0.43) NPSR1KMT2APOLBAPEX1ATM
SCHEMBL7949769 0.78 L3MBTL1 (0.51) NPSR1KMT2AATML3MBTL1TDP1
SCHEMBL7949843 0.76 NPSR1 (0.57) NPSR1KMT2APOLBAPEX1ATM
SCHEMBL7949822 0.76 NPSR1 (0.74) NPSR1KMT2APOLBAPEX1ATM
SCHEMBL7953611 0.73 NPSR1 (0.67) NPSR1KMT2APOLBAPEX1ATM
SCHEMBL7941810 0.73 POLB (0.45) NPSR1KMT2APOLBAPEX1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6255517-B1 6-SULFONYLOXYISOPROPENYL-M-CRESOL AND ESTERS Zee, Ok Pyo (KR) 2001-07-03 US disclosed