SCHEMBL7948205

SCHEMBL7948205

Cc1c(C(=O)c2cnn(C(C)(C)C)c2O)ccc(S(C)(=O)=O)c1-c1ccc(O)cc1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MELK Q14680 1/20 0.33
SENP1 Q9P0U3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7949475 0.93 MELK (0.34) MELK
SCHEMBL5000921 0.91 MAPK1 (0.35)
SCHEMBL7948308 0.88 PTGS2 (0.32)
SCHEMBL7947385 0.88 PTGS2 (0.36)
SCHEMBL7949538 0.86 FYN (0.32)
SCHEMBL7946227 0.85 PDE4B (0.36)
SCHEMBL7939850 0.83 RIPK2 (0.40)
SCHEMBL7947430 0.82
SCHEMBL7939774 0.82 PTGS2 (0.36)
SCHEMBL7951450 0.81 GAA (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265606-B1 TO CONTROL A BROAD SPECTRUM OF UNDESIRABLE VEGETATION, ARE SELECTIVE TO MAJOR CROPS, HAVE DESIRABLE ENVIRONMENTAL PROFILES, DOW AGROSCIENCES LLC 2001-07-24 US disclosed
US-6010981-A 1-alkyl-4-benzoyl-5-hydroxypyrazole compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 2000-01-04 US disclosed