Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815997 | 0.78 | TLR8 (0.58) | TLR8MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL6819187 | 0.78 | TLR8 (0.71) | TLR8MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7945583 | 0.74 | KMT2A (0.49) | TLR8MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL17664286 | 0.74 | MEN1 (0.70) | TLR8MEN1KMT2ATDP1NPC1 | |
| SCHEMBL6816005 | 0.73 | TLR8 (0.55) | TLR8MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL4825016 | 0.72 | KMT2A (0.83) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL7948395 | 0.72 | MEN1 (0.52) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL6811322 | 0.72 | TLR8 (0.68) | TLR8MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7950745 | 0.72 | MEN1 (0.51) | MEN1KMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL11141981 | 0.71 | MEN1 (0.59) | TLR8MEN1KMT2ATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |