Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359908 | 0.85 | NPC1 (0.66) | MEN1KMT2ATDP1EPHX2SMN1; SMN2 | |
| Chlotrifmeuron SCHEMBL10868747 | 0.84 | TDP1 (0.70) | MEN1KMT2ATDP1EPHX2SMN1; SMN2 | |
| SCHEMBL11137549 | 0.84 | EPHX2 (0.57) | MEN1KMT2ATDP1EPHX2SMN1; SMN2 | |
| SCHEMBL11138342 | 0.84 | RAB9A (0.64) | MEN1KMT2ATDP1EPHX2SMN1; SMN2 | |
| Penfluron SCHEMBL117735 | 0.84 | EPHX2 (0.60) | MEN1KMT2AEPHX2PTGS1RAB9A | |
| SCHEMBL22092991 | 0.83 | GPR27 (0.62) | MEN1KMT2AEPHX2RAB9ANPC1 | |
| SCHEMBL7627138 | 0.82 | TDP1 (0.75) | MEN1KMT2ATDP1EPHX2TLR8 | |
| SCHEMBL9326300 | 0.82 | EPHX2 (0.57) | MEN1KMT2AEPHX2PTGS1RAB9A | |
| SCHEMBL6819187 | 0.81 | TLR8 (0.71) | MEN1KMT2ATDP1TLR8SMN1; SMN2 | |
| SCHEMBL9503789 | 0.81 | TRPV1 (0.49) | MEN1KMT2ATDP1TLR8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399152-A | Substituted benzoyl ureas as insecticides | DUPHAR INTERNATIONAL B.V. (NL) | 1983-08-16 | — | — | US | disclosed |