Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819252 | 0.81 | SCN2A (0.48) | SHMT2LMNAKMT2AMEN1MAPT | |
| SCHEMBL6811061 | 0.80 | KMT2A (0.43) | SHMT2LMNAKMT2AMEN1MAPT | |
| SCHEMBL6816575 | 0.78 | KMT2A (0.55) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL6811724 | 0.77 | MAPT (0.45) | SHMT2LMNAKMT2AMEN1MAPT | |
| SCHEMBL27484291 | 0.76 | ALDH1A1 (0.57) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL6815692 | 0.76 | MEN1 (0.50) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7981251 | 0.76 | ALDH1A1 (0.49) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL6811079 | 0.73 | MAPT (0.42) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL6815677 | 0.71 | PARP1 (0.50) | SHMT2LMNAKMT2AMAPTKDM4E | |
| SCHEMBL6815087 | 0.71 | MEN1 (0.47) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |