Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.73 |
| ▸ | RAB9A | P51151 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | RAD52 | P43351 | 2/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL24409 | 0.82 | HTT (0.94) | HTTKMT2ADNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL5602028 | 0.82 | HTT (0.94) | HTTKMT2ADNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL18139636 | 0.82 | HTT (0.94) | HTTKMT2ADNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL6141885 | 0.82 | HTT (0.94) | HTTKMT2ADNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL8157421 | 0.82 | HTT (0.94) | HTTKMT2ADNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL25287222 | 0.82 | HTT (0.94) | HTTKMT2ADNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL219833 | 0.82 | HTT (0.94) | HTTKMT2ADNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL22436441 | 0.82 | HTT (0.94) | HTTKMT2ADNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL22206819 | 0.82 | HTT (0.94) | HTTKMT2ADNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL8156727 | 0.82 | HTT (0.94) | HTTKMT2ADNM1HSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200369-B1 | WATER, COLORANT AND AMINE CONTAINING ADDITIVE | XEROX CORPORATION | 2001-03-13 | — | — | US | disclosed |