Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SQLE | Q14534 | 6/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14000207 | 0.87 | KMT2A (0.41) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Squalene SCHEMBL27987791 | 0.82 | KMT2A (0.85) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL321568 | 0.80 | — | — | |
| SCHEMBL13312925 | 0.79 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL16690516 | 0.79 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL18327943 | 0.76 | KMT2A (0.60) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL14365717 | 0.76 | KMT2A (0.60) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23802597 | 0.75 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL21639794 | 0.75 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Squalene SCHEMBL21823197 | 0.75 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262029-B1 | TRITERPENE AGLYCONE CORE SUBSTITUTED AT POSITIONS 3 AND 28 WITH A MONOSACCHARIDE OR AN OLIGOSACCHARIDE WHICH CAN BE THE SAME OR DIFFERENT, AND HAVING AN ALDEHYDE GROUP ATTACHED TO THE CORE, PREFERABLY AT THE 4-POSITION. | GALENICA PHARMACEUTICALS, INC. | 2001-07-17 | — | — | US | disclosed |
| WO-2000009075-A2 | CHEMICALLY MODIFIED SAPONINS AND THE USE THEREOF AS ADJUVANTS | GALENICA PHARMACEUTICALS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |