SCHEMBL23802597

SCHEMBL23802597

CC(C)=CCC/C(C)=C/CC/C=C(\C)CCC=C(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 1.00
▸ SQLE Q14534 8/20 0.81
▸ MAPT P10636 2/20 0.76
▸ MEN1 O00255 2/20 0.76
▸ CYP3A4 P08684 2/20 0.76
▸ ALOX15 P16050 2/20 0.76
▸ ALDH1A1 P00352 1/20 0.76
▸ UGT1A1 P22309 1/20 0.76
▸ KDM4E B2RXH2 1/20 0.67
▸ FNTA P49354 1/20 0.59
▸ FNTB P49356 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Squalene SCHEMBL31125292 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
Squalene SCHEMBL890053 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
Squalene SCHEMBL8819997 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
SCHEMBL39067 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
Squalene SCHEMBL2799805 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
Squalene SCHEMBL4444267 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
SCHEMBL8013144 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
SCHEMBL21639794 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
Squalene SCHEMBL21823197 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4
Squalene SCHEMBL29525662 1.00 KMT2A (1.00) KMT2ASQLEMAPTMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105063069-A Common andrographis herb geranyl and geranyl pyrophosphate synthase gene UNIV JIANGXI TRAD CHINESE MED 2015-11-18 — — CN claimed
CN-101186912-A Method for increasing terpene lactone content of gingkgo callus by employing trans-ggpps gene UNIV SHANGHAI JIAOTONG (CN) 2008-05-28 — — CN claimed
WO-2023121570-A2 METHOD FOR PROMOTING PLANT GROWTH NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2023-06-29 — — WO disclosed
CN-115376615-A Mining and analyzing method of Brazilian rubber tree terpene synthase gene family based on whole genome sequence 广东工业大学 2022-11-22 — — CN disclosed
US-20210285016-A1 METHODS OF MAKING AND USING E,Z,E-GERANYLGERANYL DIPHOSPHATE WISYS TECHNOLOGY FOUNDATION, INC. 2021-09-16 — — US disclosed
CN-103627717-B Chinese herbaceous peony deoxy-D-xylulose sugar-5-phosphate synthase (PLDXS) gene and coded product thereof and application INSTITUTE OF CHINESE MATERIA MEDICA, CHINA ACADEMY OF CHINESE MEDICAL SCIENCES (CN) 2016-03-23 — — CN disclosed
CN-105331518-A Apparatus for making bio-organic compounds AMYRIS BIOTECHNOLOGIES INC 2016-02-17 — — CN disclosed
CN-105063069-A Common andrographis herb geranyl and geranyl pyrophosphate synthase gene UNIV JIANGXI TRAD CHINESE MED 2015-11-18 — — CN disclosed
CN-103732753-A Recombinant production of steviol glycosides EVOLVA SA 2014-04-16 — — CN disclosed
CN-103627717-A Paeonia lactiflora 1-deoxy-D-xylulose-5-phosphate synthase (PLDXS) gene, coding products thereof and applications thereof INST CHINESE MATERIA MEDICA CHINA ACADEMY OF CMS 2014-03-12 — — CN disclosed
CN-1688697-B Homogentisate prenyl transferase ('HPT') nucleic acids and polypeptides, and uses thereof MONSANTO TECHNOLOGY LLC 2013-04-24 — — CN disclosed
CN-101186912-A Method for increasing terpene lactone content of gingkgo callus by employing trans-ggpps gene UNIV SHANGHAI JIAOTONG (CN) 2008-05-28 — — CN disclosed
CN-1688697-A Homogentisate prenyl transferase ('HPT') nucleic acids and polypeptides, and uses thereof MONSANTO TECHNOLOGY LLC (US) 2005-10-26 — — CN disclosed
CN-1685040-A Seed-specific USP promoter for expressing genes in plants MONSANTO TECHNOLOGY LLC (US) 2005-10-19 — — CN disclosed
CN-1607253-A Fermentative carotenoid production DSM IP ASSETS BV (NL) 2005-04-20 — — CN disclosed
CN-1578835-A Aromatic methyltransferase and uses thereof MONSANTO TECHNOLOGY LLC (US) 2005-02-09 — — CN disclosed
CN-1183256-C Enhanced carotenoid accumulation in storge organs of genetically engineered plants ����˹���ͱ� 2005-01-05 — — CN disclosed
CN-1168828-C Carotenoid Fermentation Production Method - 2004-09-29 — — CN disclosed
CN-1227609-A Process for producing carotenoid compounds and specialty oils in plant seeds CALGENE INC (US) 1999-09-01 — — CN disclosed
CN-1141952-A Carotenoid Fermentation Production Method HOFFMANN LA ROCHE (CH) 1997-02-05 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210285016-A1 METHODS OF MAKING AND USING E,Z,E-GERANYLGERANYL DIPHOSPHATE GGPS1, COASY, FDPS KMT2A 2994/4885SQLE 42/4885MAPT 4736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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