Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 17/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959646 | 0.83 | NPY1R (0.60) | NPY1RTP53 | |
| SCHEMBL7960716 | 0.83 | NPY1R (0.60) | NPY1R | |
| SCHEMBL7948644 | 0.81 | NPY1R (0.60) | NPY1R | |
| SCHEMBL7958925 | 0.78 | NPY1R (0.71) | NPY1RKMT2AKDM4EALOX15TSHR | |
| SCHEMBL7958718 | 0.78 | NPY1R (0.62) | NPY1RMEN1NPC1GAAMAPT | |
| SCHEMBL7959355 | 0.76 | NPY1R (0.59) | NPY1R | |
| SCHEMBL7949133 | 0.76 | NPY1R (0.65) | NPY1RMEN1NPC1GAAMAPT | |
| SCHEMBL7958788 | 0.76 | NPY1R (0.62) | NPY1RMEN1NPC1GAAMAPT | |
| SCHEMBL7958833 | 0.75 | NPY1R (0.61) | NPY1RKMT2A | |
| SCHEMBL7958879 | 0.75 | NPY1R (0.61) | NPY1RMEN1NPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |