SCHEMBL7948644

SCHEMBL7948644

Cn1c(COc2ccc(Cl)cc2)c(C(=O)CCC2CCNCC2)c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 18/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7959646 0.91 NPY1R (0.60) NPY1R
SCHEMBL7958833 0.89 NPY1R (0.61) NPY1R
SCHEMBL7960770 0.89 NPY1R (0.65) NPY1R
SCHEMBL7959209 0.85 NPY1R (0.57) NPY1R
SCHEMBL7960710 0.84 NPY1R (0.66) NPY1R
SCHEMBL7958904 0.83 NPY1R (0.71) NPY1R
SCHEMBL7958920 0.83 NPY1R (0.71) NPY1R
SCHEMBL7960712 0.83 NPY1R (0.53) NPY1R
SCHEMBL7959355 0.82 NPY1R (0.59) NPY1R
SCHEMBL7948640 0.81 NPY1R (0.54) NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6245761-B1 NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS ELI LILLY AND COMPANY 2001-06-12 US disclosed
CN-1173867-A Indolyl neuropeptide Y receptor antagonists LILLY CO ELI (US) 1998-02-18 CN disclosed