Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | RARG | P13631 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081344 | 0.83 | TRPV1 (0.39) | APEX1TRPV1RXRARXRBRXRG | |
| SCHEMBL8928288 | 0.80 | TRPV1 (0.39) | APEX1TRPV1RXRARXRBRXRG | |
| SCHEMBL7638296 | 0.80 | APEX1 (0.36) | APEX1TRPV1 | |
| SCHEMBL8026135 | 0.78 | APEX1 (0.37) | APEX1TRPV1RXRARXRBRXRG | |
| SCHEMBL8023433 | 0.75 | APEX1 (0.44) | APEX1TRPV1RXRARXRBRXRG | |
| SCHEMBL3106072 | 0.74 | CYP2D6 (0.36) | CYP2C19ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11655989 | 0.73 | APEX1 (0.46) | APEX1L3MBTL1MAPTTDP1 | |
| SCHEMBL28017837 | 0.73 | TRPV1 (0.40) | APEX1TRPV1RXRARXRBRXRG | |
| SCHEMBL6458781 | 0.73 | TRPV1 (0.41) | APEX1TRPV1RXRARXRBRXRG | |
| SCHEMBL76989 | 0.73 | APEX1 (0.50) | APEX1RXRARXRBRXRGCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6231804-B1 | USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | disclosed |