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SCHEMBL7638296

SCHEMBL7638296

CC(C)(C)c1ccc(OC(=O)c2cc(C(C)(C)C)c(OC(c3c(C(C)(C)C)cc(C(=O)Oc4ccc(C(C)(C)C)cc4C(C)(C)C)cc3C(C)(C)C)C(CO)(COP(O)O)COP(O)O)c(C(C)(C)C)c2)c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ APEX1 P27695 1/20 0.36
▸ TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9356038 0.91 APEX1 (0.40) APEX1TRPV1
SCHEMBL8026135 0.89 APEX1 (0.37) APEX1TRPV1
SCHEMBL1074117 0.83 RXRA (0.31) —
SCHEMBL10576609 0.81 LMNA (0.31) —
SCHEMBL7948650 0.80 APEX1 (0.38) APEX1TRPV1
SCHEMBL9322618 0.80 MAPK1 (0.38) —
SCHEMBL15090602 0.78 — —
SCHEMBL8644112 0.78 — —
SCHEMBL7638822 0.77 ESR1 (0.40) —
SCHEMBL1790604 0.77 HSPA5 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0856526-B1 OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PRODUCING THE SAME, CATALYST FOR (CO)POLYMERIZING OLEFIN, AND PROCESS FOR PRODUCING THE SAME CHISSO CORP (JP) 2002-08-28 — — EP disclosed
US-6313225-B2 High melt tension, high crystallization temperature; hollow moldings CHISSO CORPORATION (JP) 2001-11-06 — — US disclosed
US-20010004657-A1 OLEFIN(CO-) POLYMER COMPOSITIONS AND METHOD FOR PRODUCING THE SAME ANDCATALYST FOR OLEFIN (CO-) POLYMERIZATION AND METHOD FOR PRODUCING THE SAME CHISSO CORPORATION (JP) 2001-06-21 — — US disclosed
US-6156845-A Polyolefin composition and method of making CHISSO CORPORATION (JP) 2000-12-05 — — US disclosed
EP-0856526-A1 OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PRODUCING THE SAME, CATALYST FOR (CO)POLYMERIZING OLEFIN, AND PROCESS FOR PRODUCING THE SAME CHISSO CORPORATION (JP) 1998-08-05 — — EP disclosed