Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956729 | 0.86 | NPY1R (0.48) | NPY1RMAPTSMN1; SMN2HPGDKMT2A | |
| SCHEMBL7956690 | 0.76 | NPY1R (0.51) | NPY1RHPGD | |
| SCHEMBL7958905 | 0.67 | NPY1R (0.60) | NPY1RXBP1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL7959693 | 0.67 | NPY1R (0.98) | NPY1RMAPTCYP1A2XBP1SMN1; SMN2 | |
| SCHEMBL30750935 | 0.67 | LMNA (0.55) | NPY1RMAPTXBP1SMN1; SMN2RAB9A | |
| SCHEMBL27374634 | 0.67 | LMNA (0.55) | NPY1RMAPTXBP1SMN1; SMN2RAB9A | |
| SCHEMBL7963527 | 0.67 | NPY1R (0.57) | NPY1RXBP1HPGDKMT2A | |
| SCHEMBL7959109 | 0.66 | TP53 (0.53) | NPY1RMAPTXBP1SMN1; SMN2RAB9A | |
| 2,4-Dichlorophenoxyacetic Acid, Methyl Ester SCHEMBL5004223 | 0.66 | MAPT (0.70) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL27479801 | 0.66 | NPY1R (0.53) | NPY1RSMN1; SMN2RAB9ATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |