Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 9/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737231 | 0.94 | PTGIR (0.56) | PTGIRSLC6A4SLC6A3 | |
| SCHEMBL7956578 | 0.86 | PTGIR (0.42) | PTGIRHTR6 | |
| SCHEMBL7956698 | 0.85 | PTGIR (0.41) | PTGIRHTR6 | |
| SCHEMBL7948766 | 0.83 | SIGMAR1 (0.47) | — | |
| SCHEMBL7736944 | 0.82 | PTGIR (0.60) | PTGIRSLC6A4SLC6A3 | |
| SCHEMBL7958526 | 0.82 | PTGIR (0.48) | PTGIRHTR6 | |
| SCHEMBL7962770 | 0.81 | MEN1 (0.43) | PTGIRHTR6 | |
| SCHEMBL7960362 | 0.80 | SIGMAR1 (0.46) | SLC6A4SLC6A3 | |
| SCHEMBL7737197 | 0.77 | PTGIR (0.45) | PTGIR | |
| SCHEMBL7739673 | 0.76 | GRM7 (0.44) | PTGIRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |