Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.47 |
| ▸ | RELA | Q04206 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24496758 | 0.78 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HPGDNFKB1 | |
| SCHEMBL24496757 | 0.78 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HPGDNFKB1 | |
| SCHEMBL29587707 | 0.78 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HPGDNFKB1 | |
| SCHEMBL2301393 | 0.77 | HDAC3 (0.55) | HDAC3HDAC1HDAC2LMNAMAPT | |
| SCHEMBL29212165 | 0.76 | HDAC3 (0.54) | HDAC3HDAC1HDAC2ALDH1A1KDM4E | |
| SCHEMBL29388635 | 0.76 | HPGD (0.49) | HDAC3HDAC1HDAC2ALDH1A1NPSR1 | |
| SCHEMBL2286036 | 0.76 | HPGD (0.49) | HDAC3HDAC1HDAC2ALDH1A1NPSR1 | |
| SCHEMBL229558 | 0.76 | HPGD (0.49) | HDAC3HDAC1HDAC2ALDH1A1NPSR1 | |
| SCHEMBL230023 | 0.76 | HPGD (0.49) | HDAC3HDAC1HDAC2ALDH1A1NPSR1 | |
| SCHEMBL27554734 | 0.76 | HPGD (0.49) | HDAC3HDAC1HDAC2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258811-B1 | ADMINISTERING RETINOIC ACID RECEPTOR AGONIST | EISAI CO., LTD. (JP) | 2001-07-10 | — | — | US | claimed |
| EP-0930075-A1 | METHODS FOR PREVENTING, INHIBITING OR TREATING GRAFT REJECTION REACTIONS IN GRAFT-VERSUS-HOST DISEASE (GVHD) AND ORGAN TRANSPLANTATION | Eisai Co., Ltd. (JP) | 1999-07-21 | — | — | EP | claimed |
| US-6258811-B1 | ADMINISTERING RETINOIC ACID RECEPTOR AGONIST | EISAI CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0930075-A1 | METHODS FOR PREVENTING, INHIBITING OR TREATING GRAFT REJECTION REACTIONS IN GRAFT-VERSUS-HOST DISEASE (GVHD) AND ORGAN TRANSPLANTATION | Eisai Co., Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |