Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29388635 | 1.00 | HPGD (0.49) | HPGDTSHRSMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL230023 | 1.00 | HPGD (0.49) | HPGDTSHRSMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL27554734 | 1.00 | HPGD (0.49) | HPGDTSHRSMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL2286036 | 1.00 | HPGD (0.49) | HPGDTSHRSMN1; SMN2HDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL3909230 | 0.98 | HPGD (0.48) | HPGDTSHRSMN1; SMN2HDAC3HDAC1 | |
| Methane SCHEMBL28850179 | 0.98 | HPGD (0.48) | HPGDTSHRSMN1; SMN2HDAC3HDAC1 | |
| Fluoride SCHEMBL30783508 | 0.98 | HPGD (0.48) | HPGDTSHRSMN1; SMN2HDAC3HDAC1 | |
| Hydrogen Sulfide SCHEMBL27481907 | 0.98 | HPGD (0.48) | HPGDTSHRSMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL5847085 | 0.90 | HPGD (0.50) | HPGDTSHRSMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL30525289 | 0.87 | HDAC3 (0.47) | HPGDTSHRHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 769 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090654-B1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | LUPIN LTD (IN) | 2025-07-09 | — | — | EP | claimed |
| CN-114981253-B | Process and intermediates for preparing chroman compounds and methods therefor | 印度鲁宾有限公司 | 2024-06-18 | — | — | CN | claimed |
| US-20230140054-A1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | LUPIN LIMITED (IN) | 2023-05-04 | — | — | US | claimed |
| CN-114981253-A | Process and intermediates for preparing chroman compounds and methods therefor | 印度鲁宾有限公司 | 2022-08-30 | — | — | CN | claimed |
| WO-2021144814-A1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | LUPIN LIMITED (IN) | 2021-07-22 | — | — | WO | claimed |
| CN-108148032-B | Preparation method and application of 3, 4-dihydro-2H-1-benzopyran-2-carboxylic acid compound | 北京海步医药科技股份有限公司 | 2019-12-13 | — | — | CN | claimed |
| CN-108148032-A | A kind of preparation method and applications of 3,4- dihydros -2H-1- chromene -2- carboxylic acid compounds | 北京海步医药科技股份有限公司 | 2018-06-12 | — | — | CN | claimed |
| EP-2351729-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE ORGANIC CARBOXYLIC ACID | MITSUBISHI GAS CHEMICAL CO (JP) | 2014-01-22 | — | — | EP | claimed |
| CN-102203047-B | Process for producing optically active organic carboxylic acid | MITSUBISHI GAS CHEMICAL CO | 2013-12-11 | — | — | CN | claimed |
| EP-1163010-B1 | HEMOGLOBIN-ANTIOXIDANT CONJUGATES | THERAPURE BIOPHARMA INC (CA) | 2012-12-12 | — | — | EP | claimed |
| US-20020035276-A1 | Method for producing chroman-carboxylic acid | KURARAY CO., LTD. (JP) | 2002-03-21 | — | — | US | claimed |
| EP-1184378-A1 | Process for producing chroman-carboxylic acid | Kuraray Co., Ltd. (JP) | 2002-03-06 | — | — | EP | claimed |
| EP-1163010-A1 | HEMOGLOBIN-ANTIOXIDANT CONJUGATES | HEMOSOL INC. (CA) | 2001-12-19 | — | — | EP | claimed |
| WO-2000056367-A1 | HEMOGLOBIN-ANTIOXIDANT CONJUGATES | HEMOSOL INC. (CA) | 2000-09-28 | — | — | WO | claimed |
| US-5658796-A | USING ENZYME DERIVED FROM SERRATIA | SEPRACHEM, INC. (US) | 1997-08-19 | — | — | US | claimed |
| WO-1996040975-A1 | OPTICAL RESOLUTION OF ALKYL CHROMAN-2-CARBOXYLATES | SEPRACHEM, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| EP-0448254-B1 | Process and intermediates for 2R-benzyl-chroman-6-carbaldehyde | PFIZER (US) | 1995-01-18 | — | — | EP | claimed |
| EP-0448254-A2 | Process and intermediates for 2R-benzyl-chroman-6-carbaldehyde | PFIZER INC. (US) | 1991-09-25 | — | — | EP | claimed |
| EP-0115142-B1 | CHROMAN COMPOUNDS | ICI AMERICAS INC. (US) | 1986-11-05 | — | — | EP | claimed |
| EP-0115142-A1 | Chroman compounds | ICI AMERICAS INC. (US) | 1984-08-08 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140054-A1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | CASR, CALCR, RYR1 | HPGD 2248/4885TSHR 261/4885SMN1; SMN2 2582/4885 |
| US-20020035276-A1 | Method for producing chroman-carboxylic acid | CDYL, DDC, CTRC | HPGD 1145/4885TSHR 822/4885SMN1; SMN2 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.