Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 11/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948983 | 0.84 | NPY1R (0.49) | NPY1RLTA4HALDH1A1MAPT | |
| SCHEMBL7956848 | 0.83 | NPY1R (0.53) | NPY1RALDH1A1MAPT | |
| SCHEMBL7963031 | 0.81 | NPY1R (0.51) | NPY1RALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7963649 | 0.81 | NPY1R (0.69) | NPY1RALDH1A1MAPT | |
| SCHEMBL7959504 | 0.81 | NPY1R (0.66) | NPY1RALDH1A1MAPT | |
| SCHEMBL7959215 | 0.80 | NPY1R (0.60) | NPY1RALDH1A1MAPT | |
| SCHEMBL7960764 | 0.80 | DRD4 (0.59) | NPY1RALDH1A1MAPT | |
| SCHEMBL7956729 | 0.76 | NPY1R (0.48) | NPY1RALDH1A1MAPT | |
| SCHEMBL7960356 | 0.73 | NPY1R (0.50) | NPY1R | |
| SCHEMBL7959128 | 0.72 | NPY1R (0.71) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |