Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NPY1R | P25929 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956848 | 0.88 | NPY1R (0.53) | MAPTNPY1RMEN1KMT2AALDH1A1 | |
| SCHEMBL7963031 | 0.86 | NPY1R (0.51) | DRD4MAPTALOX12L3MBTL1NPY1R | |
| SCHEMBL7959504 | 0.85 | NPY1R (0.66) | MAPTL3MBTL1NPY1RTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL7963649 | 0.83 | NPY1R (0.69) | MAPTNPY1RALDH1A1 | |
| SCHEMBL7959215 | 0.82 | NPY1R (0.60) | MAPTALOX12L3MBTL1NPY1RTSHR | |
| SCHEMBL7963653 | 0.82 | NPY1R (0.72) | DRD4NPY1RALDH1A1 | |
| SCHEMBL7948981 | 0.80 | NPY1R (0.51) | MAPTNPY1RALDH1A1 | |
| SCHEMBL7959104 | 0.77 | NPY1R (0.73) | DRD4MAPTL3MBTL1NPY1RMEN1 | |
| SCHEMBL7960356 | 0.76 | NPY1R (0.50) | NPY1R | |
| SCHEMBL7948983 | 0.75 | NPY1R (0.49) | MAPTNPY1RTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |