Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959897 | 0.82 | NPY1R (0.54) | NPY1RALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL7963210 | 0.82 | NPY1R (0.54) | NPY1RALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL7948988 | 0.80 | NPY1R (0.52) | NPY1RALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL7959181 | 0.79 | NPY1R (0.59) | NPY1RALDH1A1HSD17B10TSHRLMNA | |
| Hydrochloric Acid SCHEMBL7956994 | 0.78 | NPY1R (0.81) | NPY1RALDH1A1HSD17B10TSHRHRH3 | |
| SCHEMBL7963250 | 0.77 | NPY1R (0.60) | NPY1RALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL7948849 | 0.76 | NPY1R (0.55) | NPY1RALDH1A1HSD17B10TSHRLMNA | |
| Hydrochloric Acid SCHEMBL7960860 | 0.75 | NPY1R (0.55) | NPY1RALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL27479065 | 0.75 | NPY1R (0.52) | NPY1RALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL27479063 | 0.75 | NPY1R (0.52) | NPY1RALDH1A1HSD17B10TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |