Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959181 | 0.84 | NPY1R (0.59) | NPY1RALDH1A1HSD17B10TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL7959359 | 0.83 | NPY1R (0.53) | NPY1RALDH1A1HSD17B10TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL7958663 | 0.78 | NPY1R (0.67) | NPY1RALDH1A1HSD17B10TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL7956994 | 0.78 | NPY1R (0.81) | NPY1RALDH1A1HSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL7960635 | 0.77 | NPY1R (0.67) | NPY1RALDH1A1HSD17B10TSHRHTT | |
| Hydrochloric Acid SCHEMBL7963120 | 0.77 | NPY1R (0.80) | NPY1RALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL7949099 | 0.77 | NPY1R (0.60) | NPY1RALDH1A1HSD17B10TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL7957069 | 0.77 | NPY1R (0.62) | NPY1RALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL7949185 | 0.76 | NPY1R (0.53) | NPY1RALDH1A1HSD17B10TSHRCHRNA7 | |
| Hydrochloric Acid SCHEMBL7960860 | 0.75 | NPY1R (0.55) | NPY1RALDH1A1HSD17B10TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | claimed |
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |