Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 0.64 |
| ▸ | RAB9A | P51151 | 13/20 | 0.64 |
| ▸ | MEN1 | O00255 | 13/20 | 0.64 |
| ▸ | NPC1 | O15118 | 12/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.64 |
| ▸ | RECQL | P46063 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 14/20 | 0.62 |
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | POLB | P06746 | 10/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | PKM | P14618 | 4/20 | 0.62 |
| ▸ | BLM | P54132 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.45 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.45 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892079 | 0.77 | KMT2A (1.00) | KMT2ARAB9AMEN1NPC1L3MBTL1 | |
| SCHEMBL1892078 | 0.77 | KMT2A (1.00) | KMT2ARAB9AMEN1NPC1L3MBTL1 | |
| SCHEMBL1893062 | 0.75 | KMT2A (0.84) | KMT2ARAB9AMEN1NPC1L3MBTL1 | |
| SCHEMBL1893060 | 0.75 | KMT2A (0.84) | KMT2ARAB9AMEN1NPC1L3MBTL1 | |
| SCHEMBL12271549 | 0.75 | KMT2A (0.84) | KMT2ARAB9AMEN1NPC1L3MBTL1 | |
| SCHEMBL12756720 | 0.64 | MEN1 (0.68) | KMT2ARAB9AMEN1NPC1L3MBTL1 | |
| SCHEMBL12319232 | 0.63 | KMT2A (1.00) | KMT2ARAB9AMEN1NPC1L3MBTL1 | |
| SCHEMBL31530568 | 0.62 | RAB9A (0.77) | KMT2ARAB9AMEN1NPC1L3MBTL1 | |
| SCHEMBL31530581 | 0.62 | RAB9A (0.77) | KMT2ARAB9AMEN1NPC1L3MBTL1 | |
| SCHEMBL8290592 | 0.62 | KMT2A (0.76) | KMT2ARAB9AMEN1NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |