Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 0.58 |
| ▸ | CCKAR | P32238 | 4/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | USP19 | O94966 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949811 | 1.00 | CCKBR (0.58) | CCKBRCCKARGRIN2BGRIN1USP19 | |
| SCHEMBL8775405 | 0.90 | CCKBR (0.54) | CCKBRCCKAR | |
| SCHEMBL8774718 | 0.83 | CCKBR (0.55) | CCKBRCCKAR | |
| SCHEMBL8774726 | 0.83 | CCKBR (0.55) | CCKBRCCKAR | |
| SCHEMBL8774491 | 0.82 | CCKBR (0.54) | CCKBRCCKAR | |
| SCHEMBL8774501 | 0.82 | CCKBR (0.54) | CCKBRCCKAR | |
| SCHEMBL8779912 | 0.82 | CCKBR (0.54) | CCKBRCCKAR | |
| SCHEMBL7544649 | 0.81 | CCKBR (0.67) | CCKBRCCKARGRIN2B | |
| SCHEMBL7544644 | 0.81 | CCKBR (0.67) | CCKBRCCKARGRIN2B | |
| SCHEMBL8774379 | 0.81 | CCKBR (0.52) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291452-B1 | CHOLECYSTOKININ ANTAGONISTS. | FUJISAWA PHARMACETICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |