Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905682 | 0.92 | MAPT (0.34) | GAALPAR1MAPTLMNAHPGD | |
| SCHEMBL7949850 | 0.91 | LPAR1 (0.41) | GAALPAR1MAPTALDH1A1RECQL | |
| SCHEMBL7960880 | 0.90 | LPAR1 (0.34) | LPAR1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL12703036 | 0.89 | MAPT (0.36) | GAALPAR1MAPTALDH1A1RECQL | |
| SCHEMBL7964600 | 0.89 | LPAR1 (0.33) | LPAR1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL7961784 | 0.89 | MAPT (0.36) | LPAR1MAPTALDH1A1 | |
| SCHEMBL7964520 | 0.88 | S1PR5 (0.33) | LPAR1MAPTNPC1RAB9ALMNA | |
| SCHEMBL7960018 | 0.88 | LPAR1 (0.37) | LPAR1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL7960049 | 0.88 | LPAR1 (0.33) | GAALPAR1ALDH1A1NPC1RAB9A | |
| SCHEMBL7960239 | 0.87 | MAPT (0.38) | LPAR1MAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |