Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949977 | 0.92 | GAA (0.37) | MAPTLPAR1GAALMNAHPGD | |
| SCHEMBL7958124 | 0.90 | SMN1; SMN2 (0.35) | MAPTLPAR1P2RX7GAAEPHX2 | |
| SCHEMBL9595651 | 0.90 | MEN1 (0.34) | MAPTP2RX7NPSR1POLBLMNA | |
| SCHEMBL8907784 | 0.88 | P2RX7 (0.34) | MAPTP2RX7GAANPSR1EPHX2 | |
| SCHEMBL8907090 | 0.87 | GPR132 (0.37) | MAPTLPAR1P2RX7THRBGAA | |
| SCHEMBL9595918 | 0.87 | MAPT (0.40) | MAPTTHRBPOLBLMNA | |
| SCHEMBL8906207 | 0.87 | P2RX7 (0.32) | LPAR1P2RX7GAANPSR1TAS1R3 | |
| SCHEMBL8906013 | 0.87 | P2RX7 (0.34) | MAPTP2RX7GAANPSR1POLB | |
| SCHEMBL8906549 | 0.87 | MAPT (0.32) | MAPTLPAR1P2RX7GAANPSR1 | |
| SCHEMBL12460527 | 0.86 | MAPT (0.32) | MAPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |