Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1782447 | 0.85 | TSHR (0.32) | TSHRGAPDH | |
| SCHEMBL1782459 | 0.82 | — | — | |
| SCHEMBL17984937 | 0.80 | — | — | |
| SCHEMBL1785890 | 0.78 | PTPN1 (0.36) | TSHRGAPDH | |
| SCHEMBL18799607 | 0.78 | PTPN1 (0.36) | TSHRGAPDH | |
| SCHEMBL5674870 | 0.78 | GAPDH (0.34) | TSHRGAPDH | |
| SCHEMBL16882890 | 0.77 | TSHR (0.40) | TSHR | |
| SCHEMBL28946275 | 0.77 | TSHR (0.40) | TSHR | |
| SCHEMBL1781121 | 0.76 | — | — | |
| SCHEMBL1782550 | 0.75 | PTPN1 (0.34) | TSHRGAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262029-B1 | TRITERPENE AGLYCONE CORE SUBSTITUTED AT POSITIONS 3 AND 28 WITH A MONOSACCHARIDE OR AN OLIGOSACCHARIDE WHICH CAN BE THE SAME OR DIFFERENT, AND HAVING AN ALDEHYDE GROUP ATTACHED TO THE CORE, PREFERABLY AT THE 4-POSITION. | GALENICA PHARMACEUTICALS, INC. | 2001-07-17 | — | — | US | claimed |
| WO-2000009075-A2 | CHEMICALLY MODIFIED SAPONINS AND THE USE THEREOF AS ADJUVANTS | GALENICA PHARMACEUTICALS, INC. (US) | 2000-02-24 | — | — | WO | claimed |