Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960121 | 0.91 | BACE1 (0.50) | BACE1 | |
| SCHEMBL7946856 | 0.91 | BACE1 (0.50) | BACE1 | |
| SCHEMBL7948793 | 0.89 | BACE1 (0.65) | BACE1 | |
| SCHEMBL12246675 | 0.89 | BACE1 (0.54) | BACE1 | |
| SCHEMBL7956220 | 0.87 | BACE1 (0.46) | BACE1 | |
| SCHEMBL7964273 | 0.85 | BACE1 (0.48) | BACE1 | |
| SCHEMBL7957144 | 0.85 | BACE1 (0.44) | BACE1 | |
| SCHEMBL12246643 | 0.85 | BACE1 (0.53) | BACE1 | |
| SCHEMBL7958619 | 0.85 | BACE1 (0.64) | BACE1 | |
| SCHEMBL7966803 | 0.84 | BACE1 (0.47) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |