Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ciaftalan SCHEMBL11520284 | 0.91 | MEN1 (0.39) | MEN1KMT2ATHRBAPEX1RECQL | |
| Ciaftalan SCHEMBL8622424 | 0.88 | MEN1 (0.40) | HPGDMAPK1NPSR1MEN1KMT2A | |
| Ciaftalan SCHEMBL9075585 | 0.86 | ELANE (0.36) | NPSR1MEN1KMT2ATHRBAPEX1 | |
| Ciaftalan SCHEMBL28514833 | 0.84 | TLR8 (0.44) | TLR7MEN1KMT2AALDH1A1TSHR | |
| Ciaftalan SCHEMBL29211555 | 0.84 | TLR8 (0.44) | TLR7MEN1KMT2AALDH1A1TSHR | |
| Ciaftalan SCHEMBL28968136 | 0.83 | TLR8 (0.43) | TLR7MEN1KMT2AALDH1A1TSHR | |
| Ciaftalan SCHEMBL16209725 | 0.83 | SLC22A1 (0.35) | MAPK1MEN1KMT2AALDH1A1HSD17B10 | |
| Ciaftalan SCHEMBL9218054 | 0.83 | MEN1 (0.43) | MAPK1NPSR1MEN1KMT2ATHRB | |
| Ciaftalan SCHEMBL5574753 | 0.82 | MEN1 (0.36) | TLR7MEN1KMT2ATHRBAPEX1 | |
| Ciaftalan SCHEMBL7996593 | 0.81 | MEN1 (0.46) | HPGDMAPK1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262005-B1 | PHTHALOCYANINE AND NAPHTHALOCYANINES COMPRISING AXIAL MOIETIES SELECTED FOR THEIR HYDROPHOBIC CHARACTER AS MEASURED BY THEIR CLOGP. | THE PROCTER & GAMBLE COMPANY | 2001-07-17 | — | — | US | disclosed |