Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ciaftalan SCHEMBL11520284 | 0.91 | MEN1 (0.39) | MEN1KMT2ATHRBAPEX1RECQL | |
| Ciaftalan SCHEMBL16209829 | 0.82 | MEN1 (0.35) | MEN1KMT2ATHRBAPEX1RECQL | |
| Ciaftalan SCHEMBL7950273 | 0.82 | HPGD (0.39) | MEN1KMT2ATHRBAPEX1RECQL | |
| Ciaftalan SCHEMBL9075585 | 0.82 | ELANE (0.36) | MEN1KMT2ATHRBAPEX1RECQL | |
| Ciaftalan SCHEMBL1392567 | 0.82 | TDP1 (0.42) | MEN1KMT2ATHRBAPEX1RECQL | |
| Ciaftalan SCHEMBL1728179 | 0.82 | MEN1 (0.46) | MEN1KMT2ATHRBAPEX1RECQL | |
| SCHEMBL813083 | 0.82 | MEN1 (0.46) | MEN1KMT2ATHRBAPEX1RECQL | |
| Ciaftalan SCHEMBL29356273 | 0.82 | MEN1 (0.46) | MEN1KMT2ATHRBAPEX1RECQL | |
| Ciaftalan SCHEMBL29360952 | 0.82 | MEN1 (0.46) | MEN1KMT2ATHRBAPEX1RECQL | |
| Ciaftalan SCHEMBL5795179 | 0.82 | MEN1 (0.46) | MEN1KMT2ATHRBAPEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106683-A2 | BIOMIMETIC IRON-OXIDE-CONTAINING LIPOPROTEIN AND RELATED MATERIALS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-09-20 | — | — | WO | disclosed |