Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 13/20 | 0.67 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.55 |
| ▸ | TPSD1 | Q9BZJ3 | 5/20 | 0.55 |
| ▸ | TPSG1 | Q9NRR2 | 5/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5637435 | 0.92 | NPY1R (0.58) | SRCNPY1RAPP | |
| SCHEMBL5637803 | 0.86 | SRC (0.52) | SRCNPY1RAPP | |
| SCHEMBL13818354 | 0.85 | SRC (0.61) | SRCTPSAB1TPSD1TPSG1 | |
| SCHEMBL5638151 | 0.84 | SRC (0.49) | SRCNPY1RAPP | |
| SCHEMBL5640916 | 0.83 | SRC (0.58) | SRCNPY1RAPP | |
| SCHEMBL27109640 | 0.82 | SRC (0.64) | SRCNPY1RAPP | |
| SCHEMBL5638695 | 0.80 | KDM4E (0.53) | SRCNPY1RAPP | |
| SCHEMBL5639237 | 0.79 | NPY1R (0.50) | SRCTPSAB1TPSD1TPSG1NPY1R | |
| SCHEMBL5638319 | 0.79 | L3MBTL1 (0.47) | SRCNPY1RAPP | |
| SCHEMBL13824487 | 0.79 | SRC (0.48) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068655-A2 | CAPROLACTAM DERIVATIVES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | disclosed |