Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16328528 | 0.72 | MEN1 (0.53) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1952387 | 0.72 | ANO1 (0.60) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3626808 | 0.71 | MEN1 (0.70) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3630632 | 0.70 | MEN1 (0.84) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3629424 | 0.70 | MEN1 (0.88) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3629758 | 0.70 | MEN1 (0.80) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12271414 | 0.69 | MEN1 (0.73) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7953938 | 0.69 | CASP3 (0.56) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12271330 | 0.69 | MEN1 (0.55) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1896255 | 0.69 | MEN1 (0.57) | ANO1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |