Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4240881 | 0.84 | USP2 (0.31) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL7621677 | 0.77 | CYP1A2 (0.64) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL7250631 | 0.77 | — | — | |
| SCHEMBL7254431 | 0.75 | LMNA (0.31) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL6124703 | 0.75 | — | — | |
| SCHEMBL6127943 | 0.75 | — | — | |
| SCHEMBL927779 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL15346368 | 0.72 | — | — | |
| SCHEMBL7252552 | 0.72 | USP2 (0.40) | USP2ALDH1A1LMNACYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL15346489 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |
| US-6281365-B1 | ANTITUMOR AGENTS | AMERICAN CYANAMID COMPANY | 2001-08-28 | — | — | US | disclosed |
| EP-0232784-B1 | (GEM-HETEROCYCLODIMETHANAMINE-N,N')PLATINUM COMPLEXES | AMERICAN CYANAMID COMPANY (US) | 1992-12-02 | — | — | EP | disclosed |
| US-4880790-A | ANTICANCER, ANTITUMOR AGENTS | AMERICAN CYANAMID COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| EP-0232784-A2 | (Gem-heterocyclodimethanamine-N,N')platinum complexes | AMERICAN CYANAMID COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |