Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 18/20 | 0.63 |
| ▸ | CTRC | Q99895 | 15/20 | 0.63 |
| ▸ | CTSG | P08311 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965289 | 0.91 | CTRC (0.73) | CMA1CTRC | |
| SCHEMBL7951168 | 0.89 | CMA1 (0.66) | CMA1CTRC | |
| SCHEMBL7962742 | 0.85 | CMA1 (0.61) | CMA1CTRC | |
| SCHEMBL5728755 | 0.83 | CMA1 (0.74) | CMA1CTRC | |
| SCHEMBL5728762 | 0.83 | CMA1 (0.74) | CMA1CTRC | |
| Hydrochloric Acid SCHEMBL5728984 | 0.81 | CMA1 (0.68) | CMA1CTRCCTSG | |
| Hydrochloric Acid SCHEMBL5728980 | 0.81 | CMA1 (0.68) | CMA1CTRCCTSG | |
| SCHEMBL6558180 | 0.80 | CTRC (0.82) | CMA1CTRCCTSG | |
| SCHEMBL6558220 | 0.79 | CTRC (0.91) | CMA1CTRCCTSG | |
| SCHEMBL7960338 | 0.79 | CMA1 (0.64) | CMA1CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271238-B1 | USEFUL IN TREATING AND PREVENTING DISEASES INVOLVING CHYMOTRYPSIN TYPE PROTEASES WHICH ARE RELATED TO ASTHMA, ALLERGY, INFLAMMATIONS, RHEUMATISM, HYPERTENSION, HEART FAILURE, MYOCARDIAL INFARCTION, AND CARDIAC HYPERTROPHY | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | claimed |
| EP-0936216-A1 | NOVEL ACETAMIDE DERIVATIVES AND PROTEASE INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-08-18 | — | — | EP | claimed |
| US-6271238-B1 | USEFUL IN TREATING AND PREVENTING DISEASES INVOLVING CHYMOTRYPSIN TYPE PROTEASES WHICH ARE RELATED TO ASTHMA, ALLERGY, INFLAMMATIONS, RHEUMATISM, HYPERTENSION, HEART FAILURE, MYOCARDIAL INFARCTION, AND CARDIAC HYPERTROPHY | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-0936216-A1 | NOVEL ACETAMIDE DERIVATIVES AND PROTEASE INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-08-18 | — | — | EP | disclosed |