Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950960 | 1.00 | EPHX2 (0.49) | EPHX2ALDH1A1LMNACNR2DGKA | |
| SCHEMBL5479283 | 0.86 | EPHX2 (0.57) | EPHX2LMNACNR2DGKAALOX5 | |
| SCHEMBL16750691 | 0.86 | EPHX2 (0.57) | EPHX2LMNACNR2DGKAALOX5 | |
| SCHEMBL5479288 | 0.86 | EPHX2 (0.57) | EPHX2LMNACNR2DGKAALOX5 | |
| SCHEMBL15506016 | 0.86 | EPHX2 (0.57) | EPHX2LMNACNR2DGKAALOX5 | |
| SCHEMBL7528574 | 0.85 | ALDH1A1 (0.51) | EPHX2ALDH1A1LMNACNR2DGKA | |
| SCHEMBL5479597 | 0.85 | EPHX2 (0.55) | EPHX2ALDH1A1LMNACNR2DGKA | |
| SCHEMBL5479599 | 0.85 | EPHX2 (0.55) | EPHX2ALDH1A1LMNACNR2DGKA | |
| SCHEMBL5807849 | 0.85 | ALDH1A1 (0.51) | EPHX2ALDH1A1LMNACNR2DGKA | |
| SCHEMBL345020 | 0.85 | EPHX2 (0.55) | EPHX2ALDH1A1LMNACNR2DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255276-B1 | MUSK MACROMOLECULE | GIVAUDEN ROURE (INTERNATIONAL) S.A. (CH) | 2001-07-03 | — | — | US | disclosed |
| EP-0908455-A1 | Macrocycles | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1999-04-14 | — | — | EP | disclosed |