Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | PYGM | P11217 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950995 | 1.00 | KMT2A (0.61) | KMT2AMEN1RCE1KDM4EIMPDH2 | |
| SCHEMBL7950988 | 1.00 | KMT2A (0.61) | KMT2AMEN1RCE1KDM4EIMPDH2 | |
| SCHEMBL7943371 | 0.91 | MEN1 (0.48) | KMT2AMEN1RCE1KDM4EALDH1A1 | |
| SCHEMBL7951576 | 0.82 | HRH4 (0.51) | HRH4PYGLPYGMHTR1ADRD2 | |
| SCHEMBL7943360 | 0.81 | HRH4 (0.56) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL7951552 | 0.80 | DRD2 (0.53) | KMT2AMEN1KDM4EIMPDH2ALDH1A1 | |
| SCHEMBL17149657 | 0.79 | KMT2A (0.72) | KMT2AMEN1RCE1KDM4EIMPDH2 | |
| SCHEMBL7950991 | 0.78 | NPC1 (0.61) | KDM4EALDH1A1HTR1ADRD2HTR2A | |
| SCHEMBL17149706 | 0.78 | KMT2A (0.71) | KMT2AMEN1RCE1KDM4EIMPDH2 | |
| SCHEMBL17149707 | 0.78 | KMT2A (0.71) | KMT2AMEN1RCE1KDM4EIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255306-B1 | PSYCHOLOGICAL DISORDERS | MACOR JOHN E (US) | 2001-07-03 | — | — | US | claimed |
| US-6255306-B1 | PSYCHOLOGICAL DISORDERS | MACOR JOHN E (US) | 2001-07-03 | — | — | US | disclosed |